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Body mass index and dynamic lung volumes in office workers.

J Coll Physicians Surg Pak. 2012 Mar;22(3):163-7. Attaur-Rasool S, Khan Shirwany TA. Department of Physiology, CMH Lahore Medical College, Lahore Cantt.

Objective: To measure the association of body mass index (BMI) to lung volumes assessed by spirometer.

Study Design: Cross-sectional analytical study.

Place and Duration of Study: Department of Physiology and Cell Biology, University of Health Sciences, Lahore, from February to August 2009.

Methodology: Two hundred and twenty-five apparently healthy adult office workers of either gender aged > 20 years were recruited. Height and weight were measured and BMI was calculated as kg/m2. Subjects were categorized as normal (BMI=18.5 to 24.9 kg/m2); overweight (BMI=25 to 29.9 kg/m2); and obese Class 1 (BMI=30 to 34.9 kg/m2) on the basis of BMI. Lung volumes were measured by digital spirometer and were reported as percentage of predicted values for forced vital capacity (FVC%), forced expiratory volume in first second (FEV1%) and ratio of FEV1 to FVC (FEV1:FVC). Groups were compared using t-test and ANOVA, correlation was assessed by Pearson's 'r'.

Results: Significant differences in lung volumes were found in different BMI categories. Obese subjects had significantly lower FVC% (p < 0.0001), as well as significantly lower FEV1% (p = 0.003) as compared to normal subjects. There were significant linear relationships between obesity and PFTs. BMI had significant negative linear association with FVC% in overweight (r = -0.197) and obese (r = - 0.488); and with FEV1% in obese subjects (r = -0.510). Gender and age had no significant effect on mean values of PFTs.

Conclusion: Obese individuals in this sample had significant decline in lung volumes

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